Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein.

Incubation of cocultures of human aortic endothelial (HAEC) and smooth muscle cells (HASMC) with LDL in the presence of 5-10% human serum resulted in a 7.2-fold induction of mRNA for monocyte chemotactic protein 1 (MCP-1), a 2.5-fold increase in the levels of MCP-1 protein in the coculture supernata...

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Detalhes bibliográficos
Main Authors: Navab, M, Imes, S S, Hama, S Y, Hough, G P, Ross, L A, Bork, R W, Valente, A J, Berliner, J A, Drinkwater, D C, Laks, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295797/
https://ncbi.nlm.nih.gov/pubmed/1752961
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