Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein.

Incubation of cocultures of human aortic endothelial (HAEC) and smooth muscle cells (HASMC) with LDL in the presence of 5-10% human serum resulted in a 7.2-fold induction of mRNA for monocyte chemotactic protein 1 (MCP-1), a 2.5-fold increase in the levels of MCP-1 protein in the coculture supernata...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Navab, M, Imes, S S, Hama, S Y, Hough, G P, Ross, L A, Bork, R W, Valente, A J, Berliner, J A, Drinkwater, D C, Laks, H
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1752961/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115532
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires