5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation.

5-Lipoxygenase (5-LO) and 5-lipoxygenase-activating protein (FLAP) are two key proteins involved in the synthesis of leukotrienes (LT) from arachidonic acid. Although both alveolar macrophages (AM) and peripheral blood leukocytes (PBL) produce large amounts of LT after activation, 5-LO translocates...

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書誌詳細
出版年:	J Clin Invest
主要な著者:	Woods, J W, Coffey, M J, Brock, T G, Singer, I I, Peters-Golden, M
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1995
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7738170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117889
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5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation.

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