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The Structure and Mechanism of the Mycobacterium tuberculosis Cyclodityrosine Synthetase

The Mycobacterium tuberculosis enzyme Rv2275 catalyzes the formation of cyclo(L-Tyr-L-Tyr) using two molecules of Tyr-tRNA(Tyr) as substrates. The three-dimensional structure of Rv2275 was determined to 2.0 Å resolution, revealing that Rv2275 is structurally related to the class Ic aminoacyl-tRNA-sy...

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Detalhes bibliográficos
Main Authors: Vetting, Matthew W., Hegde, Subray S., Blanchard, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957485/
https://ncbi.nlm.nih.gov/pubmed/20852636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.440
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