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Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis
The biosynthetic pathway of the branched-chain amino acids is essential for Mycobacterium tuberculosis growth and survival. We report here the kinetic and chemical mechanism of the pyridoxal 5′-phosphate (PLP)-dependent branched-chain aminotransferase, IlvE, from M. tuberculosis (MtIlvE). This enzym...
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| Publicat a: | Biochemistry |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443349/ https://ncbi.nlm.nih.gov/pubmed/27780341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00928 |
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