Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase stimulator, BAY 41-8543, are modulated by nitric oxide

BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC). Responses to intravenous injections of BAY 41-8543 were investigated under baseline and elevated tone conditions and when NO synthase (NOS) was inhibited with N(ω)-nitro-l-arginine methyl ester (l-NAME). Und...

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Main Authors: Badejo, Adeleke M., Nossaman, Vaughn E., Pankey, Edward A., Bhartiya, Manish, Kannadka, Chandrika B., Murthy, Subramanyam N., Nossaman, Bobby D., Kadowitz, Philip J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2010
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957355/
https://ncbi.nlm.nih.gov/pubmed/20639220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01101.2009
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