Loss of Kit(low) progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice

Gastrointestinal functions decline with ageing leading to impaired quality of life, and increased morbidity and mortality. Neurodegeneration is believed to underlie ageing-associated dysmotilities but the mechanisms have not been fully elucidated. We used progeric mice deficient in the anti-ageing p...

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Détails bibliographiques
Auteurs principaux: Izbeki, Ferenc, Asuzu, David T, Lorincz, Andrea, Bardsley, Michael R, Popko, Laura N, Choi, Kyoung Moo, Young, David L, Hayashi, Yujiro, Linden, David R, Kuro-o, Makoto, Farrugia, Gianrico, Ordog, Tamas
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2010
Sujets:
Alimentary
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956948/
https://ncbi.nlm.nih.gov/pubmed/20581042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191023
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