Loss of Kit(low) progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice

Gastrointestinal functions decline with ageing leading to impaired quality of life, and increased morbidity and mortality. Neurodegeneration is believed to underlie ageing-associated dysmotilities but the mechanisms have not been fully elucidated. We used progeric mice deficient in the anti-ageing p...

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Detalhes bibliográficos
Main Authors: Izbeki, Ferenc, Asuzu, David T, Lorincz, Andrea, Bardsley, Michael R, Popko, Laura N, Choi, Kyoung Moo, Young, David L, Hayashi, Yujiro, Linden, David R, Kuro-o, Makoto, Farrugia, Gianrico, Ordog, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Alimentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956948/
https://ncbi.nlm.nih.gov/pubmed/20581042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191023
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