Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.

This study is an attempt to determine whether estrogen could directly regulate human gonadotropin-releasing hormone (GnRH) gene expression. Human GnRH expression vectors were constructed by fusing various 5' flanking regions of the human GnRH gene upstream of the luciferase reporter gene (LUC)...

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Publicat a:J Clin Invest
Autors principals: Radovick, S, Ticknor, C M, Nakayama, Y, Notides, A C, Rahman, A, Weintraub, B D, Cutler, G B, Wondisford, F E
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115479
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