Thyrotropin-releasing hormone regulation of human TSHB expression: role of a pituitary-specific transcription factor (Pit-1/GHF-1) and potential interaction with a thyroid hormone-inhibitory element.

Regulation of human thyrotropin beta subunit gene (TSHB) expression by thyrotropin-releasing hormone (TRH) was examined in a clonal rat pituitary-cell line (GH3). Transient expression studies were done with various 5'-flanking DNA sequences of TSHB coupled to reporter gene chloramphenicol acety...

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Detalhes bibliográficos
Main Authors: Steinfelder, H J, Hauser, P, Nakayama, Y, Radovick, S, McClaskey, J H, Taylor, T, Weintraub, B D, Wondisford, F E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51399/
https://ncbi.nlm.nih.gov/pubmed/1901656
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