Thyrotropin-releasing hormone regulation of human TSHB expression: role of a pituitary-specific transcription factor (Pit-1/GHF-1) and potential interaction with a thyroid hormone-inhibitory element.

Regulation of human thyrotropin beta subunit gene (TSHB) expression by thyrotropin-releasing hormone (TRH) was examined in a clonal rat pituitary-cell line (GH3). Transient expression studies were done with various 5'-flanking DNA sequences of TSHB coupled to reporter gene chloramphenicol acetyltran...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Steinfelder, H J, Hauser, P, Nakayama, Y, Radovick, S, McClaskey, J H, Taylor, T, Weintraub, B D, Wondisford, F E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51399/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3130
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