Desensitization, trafficking and resensitization of the pituitary thyrotropin-releasing hormone receptor
The pituitary receptor for thyrotropin-releasing hormone (TRH) is a calcium-mobilizing G protein-coupled receptor (GPCR) that signals through Gq/11, elevating calcium and activating protein kinase C. TRH receptor signaling is quickly desensitized as a consequence of receptor phosphorylation, arresti...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2012-12-01
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| Schriftenreihe: | Frontiers in Neuroscience |
| Schlagworte: | |
| Online-Zugang: | http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00180/full |
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