Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.

This study is an attempt to determine whether estrogen could directly regulate human gonadotropin-releasing hormone (GnRH) gene expression. Human GnRH expression vectors were constructed by fusing various 5' flanking regions of the human GnRH gene upstream of the luciferase reporter gene (LUC) or th...

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Pubblicato in:	J Clin Invest
Autori principali:	Radovick, S, Ticknor, C M, Nakayama, Y, Notides, A C, Rahman, A, Weintraub, B D, Cutler, G B, Wondisford, F E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295693/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939651/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115479
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