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Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene.

This study is an attempt to determine whether estrogen could directly regulate human gonadotropin-releasing hormone (GnRH) gene expression. Human GnRH expression vectors were constructed by fusing various 5' flanking regions of the human GnRH gene upstream of the luciferase reporter gene (LUC)...

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Detalhes bibliográficos
Main Authors: Radovick, S, Ticknor, C M, Nakayama, Y, Notides, A C, Rahman, A, Weintraub, B D, Cutler, G B, Wondisford, F E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295693/
https://ncbi.nlm.nih.gov/pubmed/1939651
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