Rescue of a Dystrophin-like Protein by Exon Skipping In Vivo Restores GABA(A)-receptor Clustering in the Hippocampus of the mdx Mouse

Dystrophin, the cytoskeletal protein whose defect is responsible for Duchenne muscular dystrophy (DMD), is normally expressed in both muscles and brain. Genetic loss of brain dystrophin in the mdx mouse model of DMD reduces the capacity for type A γ-aminobutyric acid (GABA(A))-receptor clustering in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vaillend, Cyrille, Perronnet, Caroline, Ros, Carine, Gruszczynski, Carole, Goyenvalle, Aurélie, Laroche, Serge, Danos, Olivier, Garcia, Luis, Peltekian, Elise
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956917/
https://ncbi.nlm.nih.gov/pubmed/20588257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.134
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados