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Overexpression of Gs alpha protein in the hearts of transgenic mice.

Alterations in beta-adrenergic receptor-Gs-adenylyl cyclase coupling underlie the reduced catecholamine responsiveness that is a hallmark of human and animal models of heart failure. To study the effect of altered expression of Gs alpha, we overexpressed the short isoform of Gs alpha in the hearts o...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gaudin, C, Ishikawa, Y, Wight, D C, Mahdavi, V, Nadal-Ginard, B, Wagner, T E, Vatner, D E, Homcy, C J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295676/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7706476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117843
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