Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase.

We previously identified a Plasmodium falciparum trophozoite cysteine proteinase (TCP) and hypothesized that it is required for the degradation of host hemoglobin by intraerythrocytic malaria parasites. To test this hypothesis and to evaluate TCP as a chemotherapeutic target, we examined the antimal...

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Pubblicato in:	J Clin Invest
Autori principali:	Rosenthal, P J, Wollish, W S, Palmer, J T, Rasnick, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115456
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