Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase.

We previously identified a Plasmodium falciparum trophozoite cysteine proteinase (TCP) and hypothesized that it is required for the degradation of host hemoglobin by intraerythrocytic malaria parasites. To test this hypothesis and to evaluate TCP as a chemotherapeutic target, we examined the antimal...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Rosenthal, P J, Wollish, W S, Palmer, J T, Rasnick, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115456
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