Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase.

We previously identified a Plasmodium falciparum trophozoite cysteine proteinase (TCP) and hypothesized that it is required for the degradation of host hemoglobin by intraerythrocytic malaria parasites. To test this hypothesis and to evaluate TCP as a chemotherapeutic target, we examined the antimal...

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Номзүйн дэлгэрэнгүй

-д хэвлэсэн:	J Clin Invest
Үндсэн зохиолчид:	Rosenthal, P J, Wollish, W S, Palmer, J T, Rasnick, D
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Clinical Investigation 1991
Нөхцлүүд:	Research Article
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1939639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115456
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