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A bivalent glycopeptide to target two putative carbohydrate binding sites on FimH

FimH is a mannose-specific bacterial lectin found on type 1 fimbriae with a monovalent carbohydrate recognition domain (CRD) that is known from X-ray studies. However, binding studies with multivalent ligands have suggested an additional carbohydrate-binding site on this protein. In order to prove t...

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Bibliografiska uppgifter
Huvudupphovsmän: Lindhorst, Thisbe K, Bruegge, Kathrin, Fuchs, Andreas, Sperling, Oliver
Materialtyp: Artigo
Språk:Inglês
Publicerad: Beilstein-Institut 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956480/
https://ncbi.nlm.nih.gov/pubmed/20978621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.90
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