XIAP acts as a switch between type I and type II FAS-induced apoptosis signalling

FAS (APO-1/CD95) and its physiological ligand, FASL, regulate apoptotic death of unwanted or dangerous cells in many tissues, functioning as a guardian against autoimmunity and cancer development1-4. Distinct cell types differ in the mechanisms by which the ‘death receptor’ FAS triggers their apopto...

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Detalhes bibliográficos
Main Authors: Jost, Philipp J., Grabow, Stephanie, Gray, Daniel, McKenzie, Mark D., Nachbur, Ueli, Huang, David C.S., Bouillet, Philippe, Thomas, Helen E., Borner, Christoph, Silke, John, Strasser, Andreas, Kaufmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956120/
https://ncbi.nlm.nih.gov/pubmed/19626005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08229
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