Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils

Neutrophils are essential players in the first-line defense against invading bacteria and fungi. Besides its antiapoptotic role, the inhibitor of apoptosis protein (IAP) family member X-linked IAP (XIAP) has been shown to regulate innate immune signaling. Whereas the role of XIAP in innate signaling...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wicki, Simone, Gurzeler, Ursina, Wei-Lynn Wong, W, Jost, Philipp J, Bachmann, Daniel, Kaufmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133978/
https://ncbi.nlm.nih.gov/pubmed/27735938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.311
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