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The many roles of FAS receptor signaling in the immune system

FAS (also known as APO-1 or CD95) belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that contain an intra-cellular ‘death domain’ and can trigger apoptosis. Its physiological ligand, FASL (CD95L), is a member of the corresponding TNF cytokine family. Studies with spontaneo...

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Detalhes bibliográficos
Main Authors: Strasser, Andreas, Jost, Philipp J, Nagata, Shigekazu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956119/
https://ncbi.nlm.nih.gov/pubmed/19239902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.01.001
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