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RNAi and small interfering RNAs in human disease therapeutic applications

Small interfering RNAs (siRNAs) have shown to effectively down-regulate gene expression in human cells, giving them potential to eradicate disease. Prospects for clinical applications are discussed in this review, along with an overview of recent history and our current understanding of siRNAs used...

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Bibliografische gegevens
Hoofdauteurs: Lares, Monica R., Rossi, John J., Ouellet, Dominique L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955826/
https://ncbi.nlm.nih.gov/pubmed/20833440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2010.07.009
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