טוען...
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
Despite the great potential of RNAi, ectopic expression of shRNA or siRNAs holds the inherent risk of competition for critical RNAi components, thus altering the regulatory functions of some cellular microRNAs. In addition, specific siRNA sequences can potentially hinder incorporation of other siRNA...
שמור ב:
| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2007
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1976469/ https://ncbi.nlm.nih.gov/pubmed/17660190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm543 |
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