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RNAi Therapeutics: Principles, Prospects and Challenges

RNA interference (RNAi) was discovered less than a decade ago and already there are human clinical trials in progress or planned. A major advantage of RNAi versus other anti-sense based approaches for therapeutic applications is that it utilizes cellular machinery that efficiently allows targeting o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Aagaard, Lars, Rossi, John J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978219/
https://ncbi.nlm.nih.gov/pubmed/17449137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2007.03.005
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