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RNAi and small interfering RNAs in human disease therapeutic applications

Small interfering RNAs (siRNAs) have shown to effectively down-regulate gene expression in human cells, giving them potential to eradicate disease. Prospects for clinical applications are discussed in this review, along with an overview of recent history and our current understanding of siRNAs used...

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Autors principals: Lares, Monica R., Rossi, John J., Ouellet, Dominique L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955826/
https://ncbi.nlm.nih.gov/pubmed/20833440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2010.07.009
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