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RNAi and small interfering RNAs in human disease therapeutic applications

Small interfering RNAs (siRNAs) have shown to effectively down-regulate gene expression in human cells, giving them potential to eradicate disease. Prospects for clinical applications are discussed in this review, along with an overview of recent history and our current understanding of siRNAs used...

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Detalles Bibliográficos
Main Authors: Lares, Monica R., Rossi, John J., Ouellet, Dominique L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955826/
https://ncbi.nlm.nih.gov/pubmed/20833440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2010.07.009
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