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Prostate cancer radiosensitization through PARP-1 hyperactivation

The clinical experimental agent, β-lapachone (Arq 501), can act as a potent radiosensitizer in vitro through an unknown mechanism. In this study, we analyzed the mechanism to determine whether β-lapachone may warrant clinical evaluation as a radiosensitizer. β-lapachone killed prostate cancer cells...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Dong, Ying, Bey, Erik A., Li, Long-Shan, Kabbani, Wareef, Yan, Jingsheng, Xie, Xian-Jin, Hsieh, Jer-Tsong, Gao, Jinming, Boothman, David A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955807/
https://ncbi.nlm.nih.gov/pubmed/20940411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1418
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