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Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis

Huntington disease (HD) is a fatal neurodegenerative disorder caused by an expanded CAG repeat. Its length can be used to estimate the time of clinical diagnosis, which is defined by overt motor symptoms. Non-motor symptoms begin before motor onset, and involve changes in hypothalamus-regulated func...

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Detalhes bibliográficos
Main Authors: Soneson, Charlotte, Fontes, Magnus, Zhou, Yongxia, Denisov, Vladimir, Paulsen, Jane S., Kirik, Deniz, Petersén, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955781/
https://ncbi.nlm.nih.gov/pubmed/20682340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.07.013
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