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The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation
BACKGROUND: ADAM17/TACE activity is important during embryonic development. We wished to investigate possible roles of this metalloprotease, focusing on vascular development. METHODOLOGY/PRINCIPAL FINDINGS: Mice mutant in the enzymatic activity of ADAM17 were examined at various stages of embryonic...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Public Library of Science
2010
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955552/ https://ncbi.nlm.nih.gov/pubmed/20976179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013433 |
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