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Interaction with PI3-kinase contributes to the cytotoxic activity of Apoptin

Apoptin, a small protein from the chicken anemia virus, has attracted attention because of its specificity in killing tumor cells. Localization of apoptin in the nucleus of tumor cells has been shown to be vital for proapoptotic activity, however, targeted expression of apoptin in the nucleus of nor...

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Bibliografiske detaljer
Main Authors: Maddika, S, Wiechec, E, Ande, SR, Poon, IK, Fischer, U, Wesselborg, S, Jans, DA, Schulze-Osthoff, K, Los, M
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954967/
https://ncbi.nlm.nih.gov/pubmed/18059340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210958
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