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Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent
Apoptin, a chicken anemia virus-derived protein, selectively induces apoptosis in transformed but not in normal cells, thus making it a promising candidate as a novel anticancer therapeutic. The mechanism of apoptin-induced apoptosis is largely unknown. Here, we report that contrary to previous assu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954965/ https://ncbi.nlm.nih.gov/pubmed/16288204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209258 |
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