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Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent

Apoptin, a chicken anemia virus-derived protein, selectively induces apoptosis in transformed but not in normal cells, thus making it a promising candidate as a novel anticancer therapeutic. The mechanism of apoptin-induced apoptosis is largely unknown. Here, we report that contrary to previous assu...

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Bibliografische gegevens
Hoofdauteurs: Burek, M, Maddika, S, Burek, CJ, Daniel, PT, Schulze-Osthoff, K, Los, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954965/
https://ncbi.nlm.nih.gov/pubmed/16288204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209258
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