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Mapping of Apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy

Majority of CHRONIC myeloid leukemia patients experience an adequate therapeutic effect from imatinib however, 26–37% of patients discontinue imatinib therapy due to a suboptimal response or intolerance. Here we investigated derivatives of apoptin, a chicken anemia viral protein with selective toxic...

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Bibliografiske detaljer
Main Authors: Jangamreddy, Jaganmohan R., Panigrahi, Soumya, Lotfi, Kourosh, Yadav, Manisha, Maddika, Subbareddy, Tripathi, Anil Kumar, Sanyal, Sabyasachi, Łos, Marek J.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196195/
https://ncbi.nlm.nih.gov/pubmed/25216532
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