Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall.

Apolipoprotein E (apoE) plays a crucial role in lipoprotein metabolism both in plasma and in peripheral tissues. To test whether apoE in the vascular wall has a direct and local effect on atherogenesis, we established transgenic mice expressing human apoE under control of H2 Ld promoter. Studies on...

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Main Authors: Shimano, H, Ohsuga, J, Shimada, M, Namba, Y, Gotoda, T, Harada, K, Katsuki, M, Yazaki, Y, Yamada, N
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC295491/
https://ncbi.nlm.nih.gov/pubmed/7860728
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