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Inhibition of diet-induced atheroma formation in transgenic mice expressing apolipoprotein E in the arterial wall.

Apolipoprotein E (apoE) plays a crucial role in lipoprotein metabolism both in plasma and in peripheral tissues. To test whether apoE in the vascular wall has a direct and local effect on atherogenesis, we established transgenic mice expressing human apoE under control of H2 Ld promoter. Studies on...

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Publicado no:J Clin Invest
Principais autores: Shimano, H, Ohsuga, J, Shimada, M, Namba, Y, Gotoda, T, Harada, K, Katsuki, M, Yazaki, Y, Yamada, N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7860728/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117687
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