Comparative analysis of four methods to extract DNA from paraffin-embedded tissues: effect on downstream molecular applications

BACKGROUND: A large portion of tissues stored worldwide for diagnostic purposes is formalin-fixed and paraffin-embedded (FFPE). These FFPE-archived tissues are an extremely valuable source for retrospective (genetic) studies. These include mutation screening in cancer-critical genes as well as patho...

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Main Authors: Huijsmans, Cornelis JJ, Damen, Jan, van der Linden, Johannes C, Savelkoul, Paul HM, Hermans, Mirjam HA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Technical Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954845/
https://ncbi.nlm.nih.gov/pubmed/20840759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-239
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