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Combinatorial Chemoprevention Reveals a Novel Smoothened Independent Role of GLI1 in Esophageal Carcinogenesis

Reflux-induced injury promotes esophageal adenocarcinoma, one of the most rapidly increasing, highly lethal cancers in Western countries. Here we investigate the efficacy of a combinatorial chemoprevention strategy for esophageal adenocarcinoma and characterize the underlying molecular mechanisms. S...

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Autors principals: Rizvi, Sumera, DeMars, Cathrine J., Comba, Andrea, Gainullin, Vladimir, Rizvi, Zaheer, Almada, Luciana L., Wang, Kenneth, Lomberk, Gwen, Fernández-Zapico, Martin E., Buttar, Navtej S.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954590/
https://ncbi.nlm.nih.gov/pubmed/20647328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0197
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