Sequence-specific Recruitment of Heterochromatin Protein 1 via Interaction with Krüppel-like Factor 11, a Human Transcription Factor Involved in Tumor Suppression and Metabolic Diseases

Heterochromatin protein 1 (HP1) proteins are “gatekeepers” of epigenetic gene silencing that is mediated by lysine 9 of histone H3 methylation (H3K9me). Current knowledge supports a paradigm whereby HP1 proteins achieve repression by binding to H3K9me marks and interacting to H3K9 histone methyltran...

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Detalhes bibliográficos
Main Authors: Lomberk, Gwen, Mathison, Angela J., Grzenda, Adrienne, Seo, Seungmae, DeMars, Cathrine J., Rizvi, Sumera, Bonilla-Velez, Juliana, Calvo, Ezequiel, Fernandez-Zapico, Martin E., Iovanna, Juan, Buttar, Navtej S., Urrutia, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339955/
https://ncbi.nlm.nih.gov/pubmed/22318730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342634
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