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ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration
We previously identified that overexpression of the platelet-derived growth factor receptor (PDGFR) is associated with metastatic medulloblastoma (MB) and showed that PDGF treatment increases ERK activity and promotes MB cell migration. In this study, we investigated whether ERK regulates Rac1/Pak1...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954413/ https://ncbi.nlm.nih.gov/pubmed/20526801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-010-9337-9 |
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