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ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration

We previously identified that overexpression of the platelet-derived growth factor receptor (PDGFR) is associated with metastatic medulloblastoma (MB) and showed that PDGF treatment increases ERK activity and promotes MB cell migration. In this study, we investigated whether ERK regulates Rac1/Pak1...

詳細記述

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書誌詳細
主要な著者: Yuan, Liangping, Santi, Mariarita, Rushing, Elisabeth J., Cornelison, Robert, MacDonald, Tobey J.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954413/
https://ncbi.nlm.nih.gov/pubmed/20526801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-010-9337-9
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