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ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration

We previously identified that overexpression of the platelet-derived growth factor receptor (PDGFR) is associated with metastatic medulloblastoma (MB) and showed that PDGF treatment increases ERK activity and promotes MB cell migration. In this study, we investigated whether ERK regulates Rac1/Pak1...

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Autors principals: Yuan, Liangping, Santi, Mariarita, Rushing, Elisabeth J., Cornelison, Robert, MacDonald, Tobey J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954413/
https://ncbi.nlm.nih.gov/pubmed/20526801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-010-9337-9
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