Tracing the Derivation of Embryonic Stem Cells from the Inner Cell Mass by Single-Cell RNA-Seq Analysis

During the transition from the inner cell mass (ICM) cells of blastocysts to pluripotent embryonic stem cells (ESCs) in vitro, a normal developmental program is replaced in cells that acquire a capacity for infinite self-renewal and pluripotency. We explored the underlying mechanism of this switch b...

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Hlavní autoři: Tang, Fuchou, Barbacioru, Catalin, Bao, Siqin, Lee, Caroline, Nordman, Ellen, Wang, Xiaohui, Lao, Kaiqin, Surani, M. Azim
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954317/
https://ncbi.nlm.nih.gov/pubmed/20452321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.03.015
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