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ATM-Dependent Phosphorylation of ATF2 Is Required for the DNA Damage Response
Activating transcription factor 2 (ATF2) is regulated by JNK/p38 in response to stress. Here, we demonstrate that the protein kinase ATM phosphorylates ATF2 on serines 490 and 498 following ionizing radiation (IR). Phosphoantibodies to ATF2(490/8) reveal dose- and time-dependent phosphorylation of A...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954254/ https://ncbi.nlm.nih.gov/pubmed/15916964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.04.015 |
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