Regulation of TIP60 by ATF2 Modulates ATM Activation

TIP60 (HTATIP) is a histone acetyltransferase (HAT) whose function is critical in regulating ataxia-telangiectasia mutated (ATM) activation, gene expression, and chromatin acetylation in DNA repair. Here we show that under non-stressed conditions, activating transcription factor-2 (ATF2) in cooperat...

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Hlavní autoři: Bhoumik, Anindita, Singha, Netai, O'Connell, Matthew J., Ronai, Ze'ev A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Protein Synthesis, Post-Translational Modification, and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427333/
https://ncbi.nlm.nih.gov/pubmed/18397884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802030200
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