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Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca(2+) Handling via a NADPH Oxidase-Dependent Mechanism

OBJECTIVES: Anthrax infection is associated with devastating cardiovascular sequelae, suggesting unfavorable cardiovascular effects of toxins originated from Bacillus anthracis namely lethal and edema toxins. This study was designed to examine the direct effect of lethal toxins on cardiomyocyte cont...

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Detalhes bibliográficos
Main Authors: Kandadi, Machender R., Hua, Yinan, Ma, Heng, Li, Qun, Kuo, Shu-ru, Frankel, Arthur E., Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954163/
https://ncbi.nlm.nih.gov/pubmed/20967205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013335
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