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Anthrax Lethal Toxin Suppresses Murine Cardiomyocyte Contractile Function and Intracellular Ca(2+) Handling via a NADPH Oxidase-Dependent Mechanism

OBJECTIVES: Anthrax infection is associated with devastating cardiovascular sequelae, suggesting unfavorable cardiovascular effects of toxins originated from Bacillus anthracis namely lethal and edema toxins. This study was designed to examine the direct effect of lethal toxins on cardiomyocyte cont...

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Auteurs principaux: Kandadi, Machender R., Hua, Yinan, Ma, Heng, Li, Qun, Kuo, Shu-ru, Frankel, Arthur E., Ren, Jun
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954163/
https://ncbi.nlm.nih.gov/pubmed/20967205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013335
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