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Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts

Chronic drinking leads to myocardial contractile dysfunction where ethanol metabolism plays an essential role. Acetaldehyde, the main ethanol metabolite, mediates alcohol-induced cell injury although the underlying mechanism is still elusive. This study was designed to examine the mechanism involved...

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Bibliografski detalji
Glavni autori: Guo, Rui, Hu, Nan, Kandadi, Machender R., Ren, Jun
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405837/
https://ncbi.nlm.nih.gov/pubmed/22441020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.18997
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