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Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts
Chronic drinking leads to myocardial contractile dysfunction where ethanol metabolism plays an essential role. Acetaldehyde, the main ethanol metabolite, mediates alcohol-induced cell injury although the underlying mechanism is still elusive. This study was designed to examine the mechanism involved...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405837/ https://ncbi.nlm.nih.gov/pubmed/22441020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.18997 |
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