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Ca(+2)/Calmodulin-Dependent Protein Kinase Mediates Glucose Toxicity-Induced Cardiomyocyte Contractile Dysfunction

(1) Hyperglycemia leads to cytotoxicity in the heart. Although several theories are postulated for glucose toxicity-induced cardiomyocyte dysfunction, the precise mechanism still remains unclear. (2) This study was designed to evaluate the impact of elevated extracellular Ca(2+) on glucose toxicity-...

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Autors principals: Zhang, Rong-Huai, Guo, Haitao, Kandadi, Machender R., Wang, Xiao-Ming, Ren, Jun
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382966/
https://ncbi.nlm.nih.gov/pubmed/22745633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/829758
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