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Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy

BACKGROUND: Lethal and edema toxins secreted by Bacillus anthracis during anthrax infection were found to incite serious cardiovascular complications. However, the underlying mechanisms in anthrax lethal toxin-induced cardiac anomalies remain unknown. This study was designed to evaluate the impact o...

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Detalhes bibliográficos
Main Authors: Kandadi, Machender R, Yu, Xuejun, Frankel, Arthur E, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3520786/
https://ncbi.nlm.nih.gov/pubmed/23134810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-134
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