Influence of Reduced Folate Carrier and Dihydrofolate Reductase Genes on Methotrexate-Induced Cytotoxicity

PURPOSE: The aim of this study is to investigate the effect of genetic variations and the expression of the reduced folate carrier (RFC) and dihydrofolate reductase (DHFR) on the drug sensitivity to methotrexate (MTX) in different cancer cell lines. MATERIALS AND METHODS: We examined the six human c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yoon, Seong-Ae, Choi, Jung Ran, Kim, Jeong-Oh, Shin, Jung-Young, Zhang, XiangHua, Kang, Jin-Hyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953780/
https://ncbi.nlm.nih.gov/pubmed/20948922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2010.42.3.163
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados